T-Coffee is distributed as precompiled binaries for Linux and Mac OSX platforms (32-bit or 64-bit) with a guided install procedure. All results presented have been reported using a 64-bit pre-compiled version. This is the smoothest and quickest way to install T-Coffee on a local machine, since it comes with all required components and does not need any special user privilege. The default installation does not require any root privilege.

Linux

• Download the installer package at http://tcoffee.org/Packages/Stable/Latest
• Grant execution permission to the downloaded file with the following command:
  

• Launch the installation wizard with:

• Follow the wizard instructions and complete the installation
• Open a new terminal session to be sure that your environment is updated.
• Type the following command to verify that the installation was successful:
  

Mac OS X

• No T-Coffee pre-compiled installer is available for the Windows operating system. Windows users need to compile and install it using the source distribution package as described below. An easier alternative is to install a Linux guest on your Windows workstation using any virtualization tool (VMware, VirtualBox, etc) and to run the linux installer on this virtual machine. Most flavors of Linux should work, Fedora, Debian, and Ubuntu being the most thoroughly tested.